Bio-functionalization of ligand-free upconverting lanthanide doped nanoparticles for bio-imaging and cell targeting.
نویسندگان
چکیده
We report on the functionalization of ligand-free NaGdF(4):Er(3+), Yb(3+) upconverting nanoparticles with heparin and basic fibroblast growth factor (bFGF). These upconverting nanoparticles are used to obtain high-contrast images of HeLa cells. These images reveal that the heparin-bFGF functionalized nanoparticles show specific binding to the cell membrane.
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عنوان ژورنال:
- Nanoscale
دوره 4 12 شماره
صفحات -
تاریخ انتشار 2012